Powell-McMullan House is a simple, but ample, frame dwelling built about 1800 that was more than doubled in size in 1842. Architectural evidence suggests that the original house was a two–story, hall-and–parlor-plan dwelling constructed during the ownership of Ruth Powell Breeden, daughter of an early settler. This section features floor-to-ceiling beaded sheathing with hand-wrought rosehead nails, pit-sawn timbers, and mortise-and-tenon joinery. The Greek Revival addition was made by Jeremiah McMullan, son of another early settler and a Methodist circuit–riding preacher. While typically plain, the Powell-McMullan House is a good example of the vernacular architecture of the area. Its picturesque setting in Greene County is framed by the Blue Ridge Mountains and the South River that flows across the property frontage.